Recombinant MCM7 antibody

Catalog No. ABIN7828393

This Rabbit Monoclonal antibody specifically detects MCM7 in WB, IHC, IF and FACS. It exhibits reactivity toward Human and Green Monkey.

Quick Overview for Recombinant MCM7 antibody (ABIN7828393)

Target: MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

Antibody Type: Recombinant Antibody

Reactivity: Human, Green Monkey

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MCM7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: A456

Product Details anti-MCM7 Antibody

Purpose: Recombinant MCM7 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human MCM7 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:2000-1:10000,IHC 1:50-1:100,IF 1:50,FCM 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for MCM7

Target: MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

Alternative Name: MCM7

Background: CDC,PNAS,P1CDC,PPP1R,P1.1-MCM,MCM,MCM7,CDC47,MCM2,P1.1-MCM3,P1CDC47,P85MCM,PNAS146,PPP1R104,formerly,homolog of,regulatory subunit 104,S. cerevisiae,CDABP0042,CDC 47,CDC47 homolog,DNA replication licensing factor MCM7,Homolog of S. cerevisiae Cdc47,MCM 2,MCM 7,MCM7 minichromosome maintenance deficient 7,MCM7_HUMAN,Minichromosome maintainence,Minichromosome Maintainence 7,Minichromosome maintenance complex component 7,Minichromosome maintenance deficient 7,Minichromosome maintenance protein 7,P1.1 MCM3,PNAS 146,Protein phosphatase 1,DNA replication licensing factor MCM7 acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for once per cell cycle DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. MCM7 is also required for S-phase checkpoint activation upon UV-induced damage. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 81 kDa

Observed MW: 81 kDa

UniProt: P33993

Pathways: DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA