Recombinant MSH2 antibody

Catalog No. ABIN7828394

The Rabbit Monoclonal anti-MSH2 antibody is suitable to detect MSH2 in samples from Human. It has been validated for WB, IHC, IF and IP.

Quick Overview for Recombinant MSH2 antibody (ABIN7828394)

Target: MSH2 (Mismatch Repair Protein 2 (MSH2))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MSH2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: A307

Product Details anti-MSH2 Antibody

Purpose: Recombinant MSH2 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human MSH2 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:1000,IHC 1:50,IF 1:50-1:100,IP 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for MSH2

Target: MSH2 (Mismatch Repair Protein 2 (MSH2))

Alternative Name: MSH2

Background: FCC,MSH,COCA,LCFS,mutS homolog,MSH2,COCA1,FCC1,HNPCC,HNPCC1,LCFS2,mutS homolog 2,COCA1,FCC1,HNPCC,HNPCC1,LCFS2,mutS homolog 2,MSH2,COCA1,FCC1,HNPCC,HNPCC1,LCFS2,This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 105 kDa

Observed MW: 104 kDa The actual band is not consistent with the expectation.

UniProt: P43246

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response