Recombinant MUC1 antibody

Catalog No. ABIN7828401

The Rabbit Monoclonal anti-MUC1 antibody (Clone A309) (ABIN7828401) specifically detects MUC1 in IHC and WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Recombinant MUC1 antibody (ABIN7828401)

Target: MUC1 (Mucin 1 (MUC1))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MUC1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Clone: A309

Product Details anti-MUC1 Antibody

Purpose: Recombinant MUC1 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human MUC1 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:1000,IHC 1:200-1:1000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for MUC1

Target: MUC1 (Mucin 1 (MUC1))

Alternative Name: MUC1

Background: MAM,CA 15,MUC,ADMCKD,ADMCKD1,CA 15-3,CD227,EMA,H23AG,KL-6,MAM6,MCD,MCKD,MCKD1,MUC-1,MUC-1/SEC,MUC-1/X,MUC1/ZD,PEM,PEMT,PUM,MUC1,CA15-3,mucin-1,CA15 3,CA153,Episialin,Carcinoma associated mucin,MUC 1,MUC1 beta,MUC1 CT,MUC1 NT,Mucin 1,Peanut reactive urinary mucin,Polymorphic epithelial mucin,Tumor associated mucin,MUC1/CA15-3 C-terminal,EMA,mucin 1,Breast carcinoma-associated antigen DF3,Cancer antigen 15-3,Carcinoma-associated mucin,Krebs von den Lungen-6,Peanut-reactive urinary mucin,Tumor-associated epithelial membrane antigen,Tumor-associated mucin,The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack.The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 17 kDa

Observed MW: 24 kDa The actual band is not consistent with the expectation.

UniProt: P15941

Pathways: Negative Regulation of intrinsic apoptotic Signaling