Recombinant Osteoactivin antibody

Catalog No. ABIN7828435

This Rabbit Monoclonal antibody specifically detects Osteoactivin in WB, IHC and FACS. It exhibits reactivity toward Human and Mouse.

Quick Overview for Recombinant Osteoactivin antibody (ABIN7828435)

Target: Osteoactivin (GPNMB)

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Osteoactivin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: A239

Product Details anti-Osteoactivin Antibody

Purpose: Recombinant GPNMB Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human GPNMB fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:1000,IHC 1:200-1:1000,FCM 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for Osteoactivin

Target: Osteoactivin (GPNMB)

Alternative Name: GPNMB

Background: UNQ,PRO,GPNMB,HGFIN,NMB,Glycoprotein nmb,Glycoprotein nmb like protein,Osteoactivin,Transmembrane glycoprotein,Transmembrane glycoprotein HGFIN,Transmembrane glycoprotein NMB,UNQ1725,PRO9925,Glycoprotein nmb like protein,Gpnmb,HGFIN,NMB,Osteoactivin,Transmembrane glycoprotein,Transmembrane glycoprotein HGFIN,Transmembrane glycoprotein NMB,The protein is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 64 kDa

Observed MW: 120,95,65 kDa The actual band is not consistent with the expectation.

UniProt: Q14956