Recombinant PPM1A antibody

Catalog No. ABIN7828500

The Rabbit Monoclonal anti-PPM1A antibody (Clone A336) (ABIN7828500) specifically detects PPM1A in WB and IHC. The antibody is reactive with Human and Mouse samples.

Quick Overview for Recombinant PPM1A antibody (ABIN7828500)

Target: PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PPM1A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: A336

Product Details anti-PPM1A Antibody

Purpose: Recombinant PPM1A Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human PPM1A fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:1000,IHC 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for PPM1A

Target: PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A))

Alternative Name: PPM1A

Background: PPM1A,PP2C-ALPHA,PP2CA,PP2Calpha,Protein Phosphatase 1A,Protein Phosphatase 2C Isoform Alpha,Protein Phosphatase IA,PPPM1A,Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. Dephosphorylates PRKAA1 and PRKAA2. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 42 kDa

Observed MW: 42 kDa

UniProt: P35813