Recombinant RAB8A antibody

Catalog No. ABIN7828515

The Rabbit Monoclonal anti-RAB8A antibody (Clone A639) (ABIN7828515) specifically detects RAB8A in WB and IHC. The antibody is reactive with Human and Green Monkey samples.

Quick Overview for Recombinant RAB8A antibody (ABIN7828515)

Target: RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))

Antibody Type: Recombinant Antibody

Reactivity: Human, Green Monkey

Host: Rabbit

Clonality: Monoclonal

Conjugate: This RAB8A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: A639

Product Details anti-RAB8A Antibody

Purpose: Recombinant Rab8A Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human Rab8A fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000-1:2000,IHC 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for RAB8A

Target: RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))

Alternative Name: Rab8A

Background: RAB,RAB8A,MEL,RAB8,AA409338,Mel transforming oncogene,Mel transforming oncogene (derived from cell line NK14),Mel transforming oncogene (derived from cell line NK14) RAB8 homolog,Mel transforming oncogene (RAB8 homolog),MGC124948,Oncogene c mel,Oncogene c-mel,RAB8A member RAS oncogene family,Ras associated protein RAB8,Ras related protein Rab 8A,Ras-related protein Rab-8A,The Rab8 GTPase is a member of the Ras superfamily that functions in protein transport and membrane restructuring. RAB8 has two isoforms, RAB8A and RAB8B, that share 40 % amino acid identity in the C-terminal variable region. RAB8 activity is regulated by specific guanine nucleotide exchange factors (GEFs), that mediate GTP loading, and GTPase activating proteins (GAPs) that convert them into the inactive GDP-bound form. RAB8 participates in recycling of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors to the dendritic spine surface as well as in the intracellular transport of the metabotropic glutamate receptor type 1 in neuronal cells. Rab8 is activated at the base of the cilium by its guanine nucleotide exchanger Rabin8. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 24 kDa

Observed MW: 24 kDa

UniProt: P61006

Pathways: M Phase, Regulation of long-term Neuronal Synaptic Plasticity, SARS-CoV-2 Protein Interactome