Recombinant SPI1 antibody

Catalog No. ABIN7828579

This Rabbit Monoclonal antibody specifically detects SPI1 in WB and IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for Recombinant SPI1 antibody (ABIN7828579)

Target: SPI1 (Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This SPI1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: A347

Product Details anti-SPI1 Antibody

Purpose: Recombinant PU.1 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human PU.1 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:2000,IHC 1:200-1:1000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for SPI1

Target: SPI1 (Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1))

Alternative Name: PU.1

Background: Spi,SPI1,31 kDa Transforming Protein,31 kDa-transforming protein,cb1086,Hematopoietic transcription factor PU.1,homolog of,mouse,oncogene spi1,PU.1,SFFV virus-induced murine erythroleukemia oncogene,SFPI1,si:by184l24.2,SPI 1,SPI 1 proto oncogene,SPI A,Spleen focus forming virus (SFFV) proviral integration oncogene spi1,Spleen focus forming virus proviral integration oncogene spi1,Transcription factor PU.1,transcription factor spi1,Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 31 kDa

Observed MW: 42 kDa The actual band is not consistent with the expectation.

UniProt: P17947

Pathways: Stem Cell Maintenance