Recombinant SOD2 antibody

Catalog No. ABIN7828593

The Rabbit Monoclonal anti-SOD2 antibody (Clone A107) (ABIN7828593) specifically detects SOD2 in WB and IHC. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for Recombinant SOD2 antibody (ABIN7828593)

Target: SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))

Antibody Type: Recombinant Antibody

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This SOD2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: A107

Product Details anti-SOD2 Antibody

Purpose: Recombinant SOD2 (Acetyl Lys68) Monoclonal Antibody

Purification: Protein A purified

Immunogen: Acetylated human histone SOD2 (Lys68) peptide

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:1000,IHC 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for SOD2

Target: SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))

Alternative Name: SOD2

Background: SOD,MVCD,superoxide dismutase,IPO-B,IPOB,MNSOD,MVCD6,Mn-SOD,SOD2,Superoxide Dismutase [Mn] Mitochondrial,superoxide dismutase 2,IPOB,IPO-B,MNSOD,Mn-SOD,MVCD6,superoxide dismutase 2,EC:1.15.1.1,mitochondrial,Superoxide dismutase [Mn],Manganese superoxide dismutase (MnSOD), also named as SOD2, is a mitochondrial detoxification enzyme that catalyzes the conversion of superoxide to hydrogen peroxide. Hydrogen peroxide is then decomposed to water by catalase, glutathione peroxidase, or peroxiredoxins. MnSOD and other enzymes involved in antioxidant defense protect cells from reactive oxygen species (ROS). Calorie restriction leads to SIRT3-mediated deacetylation of MnSOD and the subsequent increase of its antioxidant activity. MnSOD also plays an essential role in mediating the protective effect of mTOR inhibition to reduce epithelial stem cell senescence. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 25 kDa

Observed MW: 20 kDa The actual band is not consistent with the expectation.

UniProt: P04179

Pathways: Sensory Perception of Sound, Transition Metal Ion Homeostasis, Negative Regulation of intrinsic apoptotic Signaling