Recombinant WHSC1 antibody

Catalog No. ABIN7828677

The Rabbit Monoclonal anti-WHSC1 antibody (Clone A601) (ABIN7828677) specifically detects WHSC1 in WB. The antibody is reactive with Human samples.

Quick Overview for Recombinant WHSC1 antibody (ABIN7828677)

Target: WHSC1 (Wolf-Hirschhorn Syndrome Candidate 1 (WHSC1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This WHSC1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: A601

Product Details anti-WHSC1 Antibody

Purpose: Recombinant WHSC1 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human WHSC1 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:1000-1:5000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for WHSC1

Target: WHSC1 (Wolf-Hirschhorn Syndrome Candidate 1 (WHSC1))

Alternative Name: WHSC1

Background: TRX,NSD,WHSC,KIAA,NSD2,KMT3F,KMT3G,MMSET,REIIBP,TRX5,WHS,WHSC1,KIAA1090,WHSC1, also known as MMSET or NSD2, is a SET domain containing histone lysine methyltransferase that can di- and trimethylate histone H3 at lysine 36 (H3K36). WHSC1 mRNA is highly expressed in embryonic tissues, especially those with high degrees of proliferation, whereas in adult tissues, the mRNA is primarily expressed in thymus and testis. WHSC1 is implicated in cellular adhesion, clonogenic growth and tumorigenicity. Its overexpression has been found in various cancers. It undergoes alternative splicing resulting in different protein isoforms. Recently WHSC1 has been identified as a critical epigenetic regulator for Tfh differentiation. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 153 kDa

Observed MW: 153 kDa

UniProt: O96028

Pathways: SARS-CoV-2 Protein Interactome