Recombinant PARP1 antibody

Catalog No. ABIN7828689

The Rabbit Monoclonal anti-PARP1 antibody (Clone A190) (ABIN7828689) specifically detects PARP1 in WB, IF, IP and FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Recombinant PARP1 antibody (ABIN7828689)

Target: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PARP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)

Clone: A190

Product Details anti-PARP1 Antibody

Purpose: Recombinant Cleaved PARP1 p85 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human Cleaved PARP1 p85 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:2000,IF 1:100-1:200,FCM 1:50-1:100,IP 1:50

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for PARP1

Target: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Alternative Name: Cleaved PARP1 p85

Background: SCA,ARTD,Poly[ADP-ribose] synthase,Poly ADP ribose polymerase,poly(ADP-ribose) polymerase,Poly [ADP-ribose] polymerase,NAD(+) ADP-ribosyltransferase,ADP-ribosyltransferase diphtheria toxin-like,pADPRT,ADPRT,ADPRT 1,ADPRT1,ARTD1,PARP,PARP-1,PPOL,pADPRT-1,PARP1,Cleaved PARP,ADP-ribosyltransferase diphtheria toxin-like 1,APOPAIN,NAD(+) ADP-ribosyltransferase 1,Poly [ADP-ribose] polymerase 1,Poly ADP ribose polymerase 1,poly(ADP-ribose) polymerase 1,Poly[ADP-ribose] synthase 1,SCA1,ADPRT,ADPRT 1,ADPRT1,ARTD1,pADPRT-1,PARP,PARP-1,poly(ADP-ribose) polymerase 1,PPOL,Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair. Mediates glutamate, aspartate, serine or tyrosine ADP-ribosylation of proteins: the ADP-D-ribosyl group of NAD+ is transferred to the acceptor carboxyl group of target residues and further ADP-ribosyl groups are transferred to the 2'-position of the terminal adenosine moiety, building up a polymer with an average chain length of 20-30 units.Serine ADP-ribosylation of proteins constitutes the primary form of ADP-ribosylation of proteins in response to DNA damage. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 85kDa

Observed MW: 89kDa The actual band is not consistent with the expectation.

UniProt: P09874

Pathways: Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location