Recombinant PARP1 antibody

Catalog No. ABIN7828690

This Rabbit Monoclonal antibody specifically detects PARP1 in WB, IHC and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for Recombinant PARP1 antibody (ABIN7828690)

Target: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PARP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: A189

Product Details anti-PARP1 Antibody

Purpose: Recombinant Cleaved PARP1 p25 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human Cleaved PARP1 p25 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:2000,IHC 1:200-1:1000,IF 1:50-1:100

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for PARP1

Target: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Alternative Name: Cleaved PARP1 p25

Background: SCA,ARTD,Poly[ADP-ribose] synthase,Poly ADP ribose polymerase,poly(ADP-ribose) polymerase,Poly [ADP-ribose] polymerase,NAD(+) ADP-ribosyltransferase,ADP-ribosyltransferase diphtheria toxin-like,pADPRT,ADPRT,ADPRT 1,ADPRT1,ARTD1,PARP,PARP-1,PPOL,pADPRT-1,PARP1,Cleaved PARP,ADP-ribosyltransferase diphtheria toxin-like 1,APOPAIN,NAD(+) ADP-ribosyltransferase 1,Poly [ADP-ribose] polymerase 1,Poly ADP ribose polymerase 1,poly(ADP-ribose) polymerase 1,Poly[ADP-ribose] synthase 1,SCA1,ADPRT,ADPRT 1,ADPRT1,ARTD1,pADPRT-1,PARP,PARP-1,poly(ADP-ribose) polymerase 1,PPOL,Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair. Mainly mediates glutamate and aspartate ADP-ribosylation of target proteins: the ADP-D-ribosyl group of NAD+ is transferred to the acceptor carboxyl group of glutamate and aspartate residues and further ADP-ribosyl groups are transferred to the 2'-position of the terminal adenosine moiety, building up a polymer with an average chain length of 20-30 units. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 25 kDa

Observed MW: 25 kDa

UniProt: P09874

Pathways: Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location