Recombinant Osteoactivin antibody

Catalog No. ABIN7829663

The Human Chimeric anti-Osteoactivin antibody is suitable to detect Osteoactivin in samples from Human. It has been validated for FACS.

Quick Overview for Recombinant Osteoactivin antibody (ABIN7829663)

Target: Osteoactivin (GPNMB)

Antibody Type: Recombinant Antibody

Fragment: Fc fragment

Reactivity: Human

Host: Human, Rabbit

Clonality: Chimeric

Conjugate: This Osteoactivin antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: 11G4

Product Details anti-Osteoactivin Antibody

Purpose: Anti-GPNMB antibody(11G4), IgG1 Chimeric mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Application Details

Application Notes: Flow Cyt 1/100

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details for Osteoactivin

Target: Osteoactivin (GPNMB)

Alternative Name: GPNMB

Background: The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.

UniProt: Q14956