MYOD1 antibody (AA 51-150)

Catalog No. ABIN740340

Product Details anti-MYOD1 Antibody

Target: MYOD1 (Myogenic Differentiation 1 (MYOD1))

Binding Specificity: AA 51-150

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYOD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse MyoD1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-MYOD1 antibody (ABIN740340)

Dai, Zhang, Wang, Liu, Li, Ding, Guo: "MicroRNA-128 regulates the proliferation and differentiation of bovine skeletal muscle satellite cells by repressing Sp1." in: Molecular and cellular biochemistry, Vol. 414, Issue 1-2, pp. 37-46, (2016) (PubMed).

Sente, Van Berendoncks, Jonckheere, Rodenburg, Lauwers, Van Hoof, Wouters, Lardon, Hoymans, Vrints: "Primary skeletal muscle myoblasts from chronic heart failure patients exhibit loss of anti-inflammatory and proliferative activity." in: BMC cardiovascular disorders, Vol. 16, pp. 107, (2016) (PubMed).

Gong, Zhao, Yang, Li, Chen, Chen, Zhou: "The control of mesenchymal stem cell differentiation using dynamically tunable surface microgrooves." in: Advanced healthcare materials, Vol. 3, Issue 10, pp. 1608-19, (2014) (PubMed).

Target Details for MYOD1

Target: MYOD1 (Myogenic Differentiation 1 (MYOD1))

Alternative Name: MyoD1 (MYOD1 Products)

Synonyms: MYF3 antibody, MYOD antibody, PUM antibody, bHLHc1 antibody, MyoD antibody, XMyoD antibody, XtmyoD antibody, mf25 antibody, myf3 antibody, pum antibody, MUF3 antibody, AI503393 antibody, Myod-1 antibody, etID309723.25 antibody, myod antibody, wu:fb57a01 antibody, zgc:136744 antibody, MYOD1 antibody, myod1 antibody, mf1 antibody, myod1-a antibody, myod1-b antibody, myogenic differentiation 1 antibody, MYOD protein antibody, myogenic factor MyoD1 antibody, myogenic differentiation 1 S homeolog antibody, myogenic differentiation 1 L homeolog antibody, MYOD1 antibody, myod1 antibody, Myod1 antibody, myod antibody, myod1.S antibody, myod1.L antibody

Background:

Synonyms: MYF3, MyoD, Myod-1, bHLHc1, AI53393, Myoblast determination protein 1, Myod1

Background: Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins.

Gene ID: 17927

UniProt: P10085

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development