ERBB3 antibody (Biotin)

Catalog No. ABIN7830259

This Mouse Monoclonal antibody specifically detects ERBB3 in FACS. It exhibits reactivity toward Human.

Quick Overview for ERBB3 antibody (Biotin) (ABIN7830259)

Target: ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ERBB3 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Clone: H3Mab-17

Product Details anti-ERBB3 Antibody (Biotin)

Purpose: Anti-Hu HER3 Biotin

Characteristics: The mouse monoclonal antibody H3Mab-17 recognizes an extracellular epitope on human HER3 (erbB3), a member of EGFR family of receptor tyrosine kinases, which is overexpressed in many cancers.

Purification: Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.

Immunogen: HER3-transfected CHO cells

Isotype: IgG2a, kappa

Application Details

Application Notes: Flow cytometry: Recommended dilution: 0.5-4 μg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for ERBB3

Target: ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

Alternative Name: HER3

Background:

NCBI Full Gene Name: erb-b2 receptor tyrosine kinase 3

Other names: ERBB3, FERLK, LCCS2

Gene name: ERBB3

Gene ID: 2065

UniProt: P21860

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway