Calnexin antibody (C-Term) (DyLight 755)

Catalog No. ABIN7830294

The DyLight 755-conjugated Goat Polyclonal anti-Calnexin antibody (ABIN7830294) specifically detects Calnexin in WB, IF and IHC (fro). The antibody is reactive with Human, Mouse, Rat, Dog and Monkey samples.

Quick Overview for Calnexin antibody (C-Term) (DyLight 755) (ABIN7830294)

Target: Calnexin (CANX)

Reactivity: Human, Mouse, Rat, Dog, Monkey

Host: Goat

Clonality: Polyclonal

Conjugate: This Calnexin antibody is conjugated to DyLight 755

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Calnexin Antibody (DyLight 755)

Binding Specificity: C-Term

Purpose: Anti-CANX, DyLight®755

Sequence: KSDAEEDGGT VSQEEEDRKP KAEEDEILNR SPRNRKPRRE

Specificity: Detects a band of 90 kDa by Western blot whole cell lysates.

Characteristics: Calnexin

Purification: Epitope affinity purified

Immunogen: Purified recombinant peptide within residues 550 aa to the C-terminus of human CANX produced in E. coli.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:5,000, IF:1:50-1:500, IHC-F:1:200-1:1,000

Restrictions: For Research Use only

Handling

Buffer: PBS, 20 % glycerol and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: The antibody solution should be gently mixed before use.

Storage: 4 °C,-20 °C

Storage Comment: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

Target Details for Calnexin

Target: Calnexin (CANX)

Alternative Name: CANX

Background:

Goat polyclonal to CANX (Calnexin) - endoplasmic reticulum (ER) membrane marker conjugated to DyLight® 755. CANX is a member of the calnexin family of molecular chaperones. This protein is a calcium-binding, ER-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.

Calnexin, CALX, CNX, FLJ26570, histocompatibility complex class I antigen binding protein p88, IP90, major histocompatibility complex class I antigen-binding protein p88, MS952, P90 antibody.

Pathways: MAPK Signaling, Thyroid Hormone Synthesis