EWSR1 antibody (N-Term)

Catalog No. ABIN7830319

This Goat Polyclonal antibody specifically detects EWSR1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog and Monkey.

Quick Overview for EWSR1 antibody (N-Term) (ABIN7830319)

Target: EWSR1 (Ewing Sarcoma Breakpoint Region 1 (EWSR1))

Reactivity: Human, Mouse, Rat, Dog, Monkey

Host: Goat

Clonality: Polyclonal

Conjugate: This EWSR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EWSR1 Antibody

Binding Specificity: N-Term

Purpose: Anti-EWSR1

Sequence: MASTDYSTYS QAAAQQGYSA YTAQPTQGYA QTTQAYGQQS YGTYGQPTDV SYTQAQTTAT YGQTAYATSY GQPPTVEGTS TGYTTPTAPQ AYSQPVQGYG TGAYDTTTAT VTTTQASYAA QSAYGTQPAY PAYGQQPAAT

Specificity: Detects endogenous levels of EWSR1 by Western blot in the whole cell lysates (HeLa, LS174T, H69, Jurkat, SHSY5Y, 3T3NIH, AtT20, etc.).

Characteristics: EWS RNA binding protein 1

Purification: Epitope affinity purified

Immunogen: Purified recombinant peptide derived from within residues 140 aa to the N-terminus of human EWSR1 produced in E. coli

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:2,000

Restrictions: For Research Use only

Handling

Buffer: PBS, 20 % glycerol and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: The antibody solution should be gently mixed before use.

Storage: 4 °C,-20 °C

Storage Comment: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

Target Details for EWSR1

Target: EWSR1 (Ewing Sarcoma Breakpoint Region 1 (EWSR1))

Alternative Name: EWSR1

Background:

Goat polyclonal antibody to EWSR1. EWSR1, or Ewing Sarcoma Breakpoint Region 1, encodes the EWS protein, a member of the FET (FUS, EWS, TAF15) family of RNA-binding proteins. These proteins are involved in various cellular processes, including gene transcription and RNA splicing. The EWS protein has a transcriptional activation domain that initiates gene transcription and an RNA-binding domain that attaches to RNA molecules. This dual functionality suggests a role in both transcription regulation and RNA processing.

EWS, EWS-FLI1, bK984G1.4 antibody.