Presenilin 1 antibody (pSer357)

Catalog No. ABIN7843171

The Rabbit Polyclonal anti-Presenilin 1 antibody is suitable to detect Presenilin 1 in samples from Human, Mouse, Rat, Monkey and Chicken. It has been validated for WB and IHC.

Quick Overview for Presenilin 1 antibody (pSer357) (ABIN7843171)

Target: Presenilin 1 (PSEN1)

Reactivity: Human, Mouse, Rat, Monkey, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Presenilin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Presenilin 1 Antibody

Binding Specificity: pSer357

Purpose: Rabbit polyclonal antibody to Presenilin 1 (Phospho-S357)

Specificity: Recognizes endogenous levels of Presenilin 1 protein only when phosphorylated at S357.

Purification: The antibody was purified by immunogen affinity chromatography.

Immunogen: KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding S357 of human Presenilin 1 protein. The exact sequence is proprietary.

Application Details

Application Notes: WB (1/500 - 1/1000), IH (1/50 - 1/200)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in 0.42 % Potassium phosphate, 0.87 % Sodium chloride, pH 7.3, 30 % glycerol, and 0.01 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

Target Details for Presenilin 1

Target: Presenilin 1 (PSEN1)

Alternative Name: PSEN1

Background: AD3, PS1, PSNL1, Presenilin-1, PS-1, Protein S182

Gene ID: 5663, 19164, 29192

UniProt: P49768

Pathways: Notch Signaling, EGFR Signaling Pathway, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport