AMH antibody

Catalog No. ABIN7849751

The Mouse Monoclonal anti-AMH antibody (Clone 1C10) (ABIN7849751) specifically detects AMH in ELISA and LF. The antibody is reactive with Human samples.

Quick Overview for AMH antibody (ABIN7849751)

Target: AMH (Anti-Mullerian Hormone (AMH))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This AMH antibody is un-conjugated

Application: ELISA, Lateral Flow (LF)

Clone: 1C10

Product Details anti-AMH Antibody

Purpose: Monoclonal Anti- Muellerian-inhibiting factor, AMH (Detection Ab)

Characteristics: This antibody may be used as in antibody pair experiments such as ELISA.

Purification: Protein A or G purified

Purity: >95 % by HPLC & SDS-PAGE

Immunogen: Recombinant protein.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.9 % NaCl without preservative.

Preservative: Without preservative

Handling Advice: Avoid repeated freeze and thaw cycles.

Storage: 4 °C

Storage Comment: Aliquot and store at 2-8°C for long term (at least one year). Avoid repeated freeze and thaw cycles.

Expiry Date: 12 months

Target Details for AMH

Target: AMH (Anti-Mullerian Hormone (AMH))

Alternative Name: Muellerian-inhibiting factor

Background: Anti-Müllerian hormone (AMH), also known as Müllerian-inhibiting hormone (MIH), is a glycoprotein hormone structurally related to inhibin and activin from the transforming growth factor beta superfamily, whose key roles are in growth differentiation and folliculogenesis. In humans, it is encoded by the AMH gene, on chromosome 19p13.3, while its receptor is encoded by the AMHR2 gene on chromosome 12.AMH is activated by SOX9 in the Sertoli cells of the male fetus. Its expression inhibits the development of the female reproductive tract, or Müllerian ducts (paramesonephric ducts), in the male embryo, thereby arresting the development of fallopian tubes, uterus, and upper vagina.

Pathways: Negative Regulation of Hormone Secretion