Recombinant CDX2 antibody

Catalog No. ABIN7857755

This Rabbit Monoclonal antibody specifically detects CDX2 in IHC. It exhibits reactivity toward Human.

Quick Overview for Recombinant CDX2 antibody (ABIN7857755)

Target: CDX2 (Caudal Type Homeobox 2 (CDX2))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CDX2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: CDX2-9298R

Product Details anti-CDX2 Antibody

Expression System: CHO Cells

Purpose: Recombinant CDX2 / Caudal Type Homeobox 2 (GI Epithelial Marker) Antibody

Specificity: The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids 79oΩand is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma.However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.

Purification: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogen: Recombinant full-length human CDX2 protein

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for CDX2

Target: CDX2 (Caudal Type Homeobox 2 (CDX2))

Alternative Name: CDX2

Background:

Caudal type homeobox 2, Caudal type homeobox transcription factor 2, Caudal-type homeobox protein 2, CDX2

HT29 cells. Human colon carcinoma

Molecular Weight: 40kDa

Gene ID: 1045, 174249

UniProt: Q99626

Pathways: Peptide Hormone Metabolism, Stem Cell Maintenance