Recombinant P-Cadherin antibody

Catalog No. ABIN7857818

This Mouse Monoclonal antibody specifically detects P-Cadherin in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for Recombinant P-Cadherin antibody (ABIN7857818)

Target: P-Cadherin (CDH3)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This P-Cadherin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: R56C1

Product Details anti-P-Cadherin Antibody

Expression System: CHO Cells

Purpose: Recombinant P-Cadherin (CDH3) (Basal Epithelial Cell Marker) Antibody

Specificity: Recognizes a protein of 116 kDa, identified as P-Cadherin-1 (CDH3). Itis a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congenital hypotrichosis with juvenile macular dystrophy.

Purification: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogen: Prokaryotic recombinant protein corresponding to a region of the external domain of the P-cadherin molecule

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for P-Cadherin

Target: P-Cadherin (CDH3)

Alternative Name: P-Cadherin

Background:

Cadherin 3 type 1, Cadherin-3, Cadp, Calcium dependent adhesion protein placental, CDH3, CDHP, HJMD, P-cadherin (Placental), PCAD, Placental cadherin

A431 or PC-3 cells. Human pancreas, placenta or prostate.

Molecular Weight: 116kDa

Gene ID: 1001, 191842

UniProt: P22223