JAZF1 antibody (AA 1-130)

Catalog No. ABIN7858233

The Mouse Monoclonal anti-JAZF1 antibody is suitable to detect JAZF1 in samples from Human. It has been validated for WB, IHC, FACS and IF.

Quick Overview for JAZF1 antibody (AA 1-130) (ABIN7858233)

Target: JAZF1 (JAZF Zinc Finger 1 (JAZF1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This JAZF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: PCRP-JAZF1-1C2

Product Details anti-JAZF1 Antibody

Binding Specificity: AA 1-130

Purpose: JAZF1 (Transcription Corepressor) Antibody

Specificity: JAZF1 (juxtaposed with another zinc finger protein 1), also known as TIP27 (TAK1-interacting protein 27) or ZNF802 (zinc finger protein 802), is a 243 amino acid protein that localizes to the nucleus and contains three C2H2-type zinc fingers. Existing as multiple alternatively spliced isoforms, JAZF1 interacts with the nuclear orphan receptor TR4 and is thought to function as a transcriptional repressor, effectively down-regulation the expression of TR4. Chromosomal aberrations in the gene encoding JAZF1 are associated with the pathogenesis of endometrial stromal tumors, suggesting a role for JAZF1 in carcinogenesis.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa1-130) of human JAZF1 protein (exact sequence is proprietary)

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for JAZF1

Target: JAZF1 (JAZF Zinc Finger 1 (JAZF1))

Alternative Name: JAZF1

Background:

DKFZp761K2222, TIP27, ZNF802

HeLa or U87 cells.Ubiquitous tissue expression.

Molecular Weight: 27.08kDa

Gene ID: 221895, 368944

UniProt: Q86VZ6