Recombinant VEGF antibody (AA 1-200)

Catalog No. ABIN7858741

The Rabbit Monoclonal anti-VEGF antibody (Clone VEGFA-7635R) (ABIN7858741) specifically detects VEGF in IHC. The antibody is reactive with Human samples.

Quick Overview for Recombinant VEGF antibody (AA 1-200) (ABIN7858741)

Target: VEGF (Vascular Endothelial Growth Factor (VEGF))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This VEGF antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: VEGFA-7635R

Product Details anti-VEGF Antibody

Binding Specificity: AA 1-200

Purpose: Recombinant VEGF (Vascular Endothelial Growth Factor) Antibody

Specificity: This MAb recognizes proteins of 19-22 kDa (reducing) and 38 kDa-44 kDa (non-reducing), identified as various isoforms of Vascular Endothelial Growth Factor or Vascular Permeability Factor (VEGF/VPF). It is highly specific to VEGF, which is a homodimeric, disulfide-linked glycoprotein with a close homology to platelet derived growth factor (PDGF). There are multiple isoforms of VEGF containing 206-, 189-, 165-, and 121-amino acid residues. The smaller two isoforms, VEGF165 and VEGF121, are secreted proteins and act as diffusible agents, whereas the larger two remain cell associated. VEGF/VPF plays an important role in angiogenesis, which promotes tumor progression and metastasis.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa1-200) of human VEGFA protein (exact sequence is proprietary)

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for VEGF

Target: VEGF (Vascular Endothelial Growth Factor (VEGF))

Alternative Name: VEGF

Background:

MVCD1, Vascular Endothelial Growth Factor A (VEGF-A), Vascular Permeability Factor (VPF), VEGFA

breast or ovarian carcinomas.|Tumor cells in astrocytomas

Molecular Weight: 19-22kDa (reducing) and 38kDa-44kDa (non-reducing)

Gene ID: 7422, 73793

UniProt: P15692