Galectin 3 antibody (AA 1-250)

Catalog No. ABIN7865301

This Mouse Monoclonal antibody specifically detects Galectin 3 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for Galectin 3 antibody (AA 1-250) (ABIN7865301)

Target: Galectin 3 (LGALS3)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Galectin 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: LGALS3-7145

Product Details anti-Galectin 3 Antibody

Binding Specificity: AA 1-250

Purpose: Galectin-3 (LGALS3) (Thyroid Cell Marker) Antibody

Specificity: Galectin-3 is a member of the beta-galactosidase-binding lectin family. It is associated with cell growth, adhesion, inflammation, mRNA processing, and apoptosis. Aberrant expression of Galectin-3 is related to malignant transformation and metastasis in carcinomas of the breast, colon and thyroid. Galectin-3 reactivity can be seen in the nucleus of neutrophils, vascular endothelium, carcinomas of the colon, breast, and thyroid. Galectin-3 may be useful in the differentiation of benign and malignant thyroid neoplasms. Galectin-3 may also be useful in the identification of certain liver disorders.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa1-250) of human LGALS3 protein (exact sequence is proprietary)

Isotype: IgG2b, lambda

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for Galectin 3

Target: Galectin 3 (LGALS3)

Alternative Name: Galectin-3

Background: Human papillary thyroid carcinoma tissue. MCF-7 cells.

Molecular Weight: 30kDa

Gene ID: 3958, 531081

UniProt: P17931

Pathways: RTK Signaling