SULT1E1 antibody (AA 100-294)

Catalog No. ABIN7858989

The Mouse Monoclonal anti-SULT1E1 antibody is suitable to detect SULT1E1 in samples from Human. It has been validated for WB and IHC.

Quick Overview for SULT1E1 antibody (AA 100-294) (ABIN7858989)

Target: SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SULT1E1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: SULT1E1-7124

Product Details anti-SULT1E1 Antibody

Binding Specificity: AA 100-294

Purpose: Sulfotransferase family 1E, estrogen-preferring, member 1 Antibody

Specificity: The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. SULT1E1, also known as STE, is a 294 amino acid member of the SULT1 family. Localized to the cytoplasm and expressed in intestine, liver and kidney, SULT1E1 exists as a homodimer that is thought to control estrogen receptor (ER) levels by sulfurylating free estradiol. Defects in the gene encoding SULT1E1 are associated with an increased risk for endometrial cancer, suggesting a role for SULT1E1 in tumorigenesis.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa100-294) of human SULT1E1 protein (exact sequence is proprietary)

Isotype: IgG2, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for SULT1E1

Target: SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))

Alternative Name: Sulfotransferase family 1E, estrogen-preferring, member 1

Background:

EST, EST-1,EST1, Estrogen sulfotransferase, estrogen-preferring, estrone sulfotransferase, ST1E1, STE, Sulfotransferase 1E1, Sulfotransferase , Sulfotransferase estrogen preferring

HEPG2 cells. Human liver|intestine or kidney.

Molecular Weight: 35kDa

Gene ID: 6783, 479898

UniProt: P49888

Pathways: Steroid Hormone Biosynthesis