MAP2 antibody (AA 1500-1700)
Quick Overview for MAP2 antibody (AA 1500-1700) (ABIN7864840)
Target
See all MAP2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 1500-1700
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Purpose
- MAP2 Antibody
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Specificity
- Microtubules, the primary component of the cytoskeletal network, interact with proteins called microtubule-associated proteins (MAPs). The microtubuleassociated proteins can be divided into two groups, structural and dynamic. The structural microtubule-associated proteins, MAP-1A, MAP-1B, MAP-2A, MAP-2B and MAP-2C, stimulate tubulin assembly, enhance microtubule stability and influence the spatial distribution of microtubules within cells. Both MAP-1 and, to a greater extent, MAP-2 have been implicated as agents of microtubule depolymerization by suppressing the dynamic instability of the microtubules. The suppression of microtubule dynamic instability by the MAP proteins is thought to be associated with phosphorylation of the MAPs.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogen
- Recombinant fragment (around aa1500-1700) of human MAP2 protein (exact sequence is proprietary)
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Isotype
- IgG1, kappa
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- MAP2 (Microtubule-Associated Protein 2 (MAP2))
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Alternative Name
- MAP2
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Background
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DKFZp686I2148, MAP dendrite specific, MAP2, MAP2A, MAP2B, MAP2C, Microtubule-associated protein 2,
Human brain.
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Molecular Weight
- 280/70kDa
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Gene ID
- 4133, 368281
Target
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