LSD1 antibody (AA 152-279)

Catalog No. ABIN7864445

The Mouse Monoclonal anti-LSD1 antibody is suitable to detect LSD1 in samples from Human. It has been validated for WB, IHC and FACS.

Quick Overview for LSD1 antibody (AA 152-279) (ABIN7864445)

Target: LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LSD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: PCRP-KDM1A-1A10

Product Details anti-LSD1 Antibody

Binding Specificity: AA 152-279

Purpose: KDM1A (Nuclear Marker &, Transcription Factor) Antibody

Specificity: This gene encodes a nuclear protein containing a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa152-279) of human KDM1A protein (exact sequence is proprietary)

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for LSD1

Target: LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))

Alternative Name: KDM1A

Background:

AOF2, BHC110, BRAF35-HDAC complex protein BHC110, BRAF35/HDAC complex, 110-kD subunit, CPRF, EC1, FAD binding protein BRAF35 HDAC complex, 110 kDa subunit, Flavin-containing amine oxidase domain-containing protein 2, LSD1, Lysine (K) specific demethylase 1A, Lysine-specific demethylase 1, Lysine-specific demethylase 1A, Lysine-specific histone demethylase 1A

HeLa cells. Ubiquitous tissue expression.

Molecular Weight: 92.9kDa

Gene ID: 23028, 591518

UniProt: O60341

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Negative Regulation of intrinsic apoptotic Signaling, Warburg Effect