Recombinant SFTPD antibody (AA 200-375)

Catalog No. ABIN7859457

The Mouse Monoclonal anti-SFTPD antibody is suitable to detect SFTPD in samples from Human. It has been validated for WB and IHC.

Quick Overview for Recombinant SFTPD antibody (AA 200-375) (ABIN7859457)

Target: SFTPD (Surfactant Protein D (SFTPD))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SFTPD antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: RSFTPD-8065

Product Details anti-SFTPD Antibody

Binding Specificity: AA 200-375

Purpose: Recombinant Pulmonary Surfactant-Associated Protein D (SFTPD) Antibody

Specificity: Pulmonary surfactant is primarily responsible for lowering the surface tension at the air-liquid interface in the alveoli, a process that is essential for normal respiration. Pulmonary surfactant is a mixture of phospholipids and proteins, including four distinct surfactant-associated proteins (SPs), SP-A, SP-B, SP-C, SP-D. SP-B and SP-C are predominantly hydrophobic proteins that associate with lipids to promote the absorption of surfactant phospholipids and to reduce the surface tension in the alveoli. SP-A and SP-D are large multimeric proteins belonging to the family of calcium-dependent lectins, designated Collectins, which contribute to the innate immune system. Both SP-A and SP-D have been shown to protect against microbial challenge through binding to the lipid components of the bacterial cell wall and facilitating the rapid removal of microbials.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa200-375) of human SFTPD protein (exact sequence is proprietary)

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for SFTPD

Target: SFTPD (Surfactant Protein D (SFTPD))

Alternative Name: Pulmonary Surfactant-Associated Protein D

Background:

COLEC7, Collectin-7, Lung surfactant protein D, PSP-D Surfactant protein D, PSPD, Pulmonary surfactant associated protein PSP-D, SFTP 4, SFTP4, SFTPD, SP-D, Surfactant associated protein pulmonary 4

Epithelial cells of the lung|Skin|small intestine or bladder. COLO38.

Molecular Weight: 43kDa

Gene ID: 6441, 253495

UniProt: P35247