Recombinant PAX5 antibody (AA 235-382)

Catalog No. ABIN7863201

The Mouse Monoclonal anti-PAX5 antibody is suitable to detect PAX5 in samples from Human and Dog. It has been validated for IHC.

Quick Overview for Recombinant PAX5 antibody (AA 235-382) (ABIN7863201)

Target: PAX5 (Paired Box 5 (PAX5))

Antibody Type: Recombinant Antibody

Reactivity: Human, Dog

Host: Mouse

Clonality: Monoclonal

Conjugate: This PAX5 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: RPAX5-4228

Product Details anti-PAX5 Antibody

Binding Specificity: AA 235-382

Purpose: Recombinant PAX5 / BSAP (Early B-Cell Marker) Antibody

Specificity: The PAX5 gene is a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding domain, known as the paired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis, therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: A recombinant fragment (around aa 235-382) of human PAX5 protein (exact sequence is proprietary)

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for PAX5

Target: PAX5 (Paired Box 5 (PAX5))

Alternative Name: PAX5

Background:

B cell lineage specific activator, BSAP, EBB-1, KLP, Paired box 5

Daudi or Ramos cells. Human tonsil, Raji, Spleen or lymph node.

Molecular Weight: 42kDa

Gene ID: 5079, 654464

UniProt: Q02548