Recombinant SFTPD antibody (AA 241-336)

Catalog No. ABIN7863390

This Rabbit Monoclonal antibody specifically detects SFTPD in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for Recombinant SFTPD antibody (AA 241-336) (ABIN7863390)

Target: SFTPD (Surfactant Protein D (SFTPD))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This SFTPD antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: SFTPD-7086R

Product Details anti-SFTPD Antibody

Binding Specificity: AA 241-336

Purpose: Recombinant Pulmonary Surfactant-Associated Protein D (SFTPD) Antibody

Specificity: Pulmonary surfactant is primarily responsible for lowering the surface tension at the air-liquid interface in the alveoli, a process that is essential for normal respiration. Pulmonary surfactant is a mixture of phospholipids and proteins, including four distinct surfactant-associated proteins (SPs), SP-A, SP-B, SP-C, SP-D. SP-B and SP-C are predominantly hydrophobic proteins that associate with lipids to promote the absorption of surfactant phospholipids and to reduce the surface tension in the alveoli. SP-A and SP-D are large multimeric proteins belonging to the family of calcium-dependent lectins, designated Collectins, which contribute to the innate immune system. Both SP-A and SP-D have been shown to protect against microbial challenge through binding to the lipid components of the bacterial cell wall and facilitating the rapid removal of microbials.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa241-336) of human SFTPD protein (exact sequence is proprietary)

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for SFTPD

Target: SFTPD (Surfactant Protein D (SFTPD))

Alternative Name: Pulmonary Surfactant-Associated Protein D

Background:

COLEC7, Collectin-7, Lung surfactant protein D, PSP-D Surfactant protein D, PSPD, Pulmonary surfactant associated protein PSP-D, SFTP 4, SFTP4, SFTPD, SP-D, Surfactant associated protein pulmonary 4

Epithelial cells of the lung, Skin, small intestine or bladder.

Molecular Weight: 43kDa

Gene ID: 6441, 253495

UniProt: P35247