IL3RA antibody (AA 26-171)

Catalog No. ABIN7859670

The Mouse Monoclonal anti-IL3RA antibody is suitable to detect IL3RA in samples from Human, Mouse, Rat and Hamster. It has been validated for WB.

Quick Overview for IL3RA antibody (AA 26-171) (ABIN7859670)

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Reactivity: Human, Mouse, Rat, Hamster

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL3RA antibody is un-conjugated

Application: Western Blotting (WB)

Clone: IL3RA-1822

Product Details anti-IL3RA Antibody

Binding Specificity: AA 26-171

Purpose: IL3RA / CD123 (Acute Myeloid Leukemia Marker) Antibody

Specificity: CD123 is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudo-autosomal region on chromosomes X or Y.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment of human IL3RA protein (around aa 26-171) (exact sequence is proprietary)

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for IL3RA

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Alternative Name: IL3RA

Background:

CD123, hIL3Ra, IL-3R-alpha, IL-3RA, IL3RAX, IL3RAY, IL3RX, IL3RY, Interleukin-3 Receptor, alpha, Interleukin3 receptor, Interleukin3 receptor, Y-chromosomal

Lymph Node or Stomach., RPMI-8226 or HDLM-2 cells. Tonsil, THP-1

Molecular Weight: 70kDa

Gene ID: 3563, 632790

UniProt: P26951

Pathways: JAK-STAT Signaling