Fibrillin 1 antibody (AA 330-476)

Catalog No. ABIN7859934

The Mouse Monoclonal anti-Fibrillin 1 antibody is suitable to detect Fibrillin 1 in samples from Human. It has been validated for IHC.

Quick Overview for Fibrillin 1 antibody (AA 330-476) (ABIN7859934)

Target: Fibrillin 1 (FBN1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Fibrillin 1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: FBN1-2191

Product Details anti-Fibrillin 1 Antibody

Binding Specificity: AA 330-476

Purpose: Fibrillin-1 (FBN1) (Marfan Syndrome Marker) Antibody

Specificity: Fibrillin-1 is an extracellular matrix glycoprotein that serves as a structural component of calcium-binding microfibrils. These microfibrils provide force-bearing structural support in elastic and non-elastic connective tissue throughout the body.Mutations in this gene are associated with Marfan syndrome.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human Fibrillin 1 fragment around aa 330-476 (Exact sequence is proprietary)

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for Fibrillin 1

Target: Fibrillin 1 (FBN1)

Alternative Name: Fibrillin-1

Background:

350 kDa glycoprotein component extracellular microfibril, ACMICD, FBN1, Fibrillin-15, Fibrillin-1, GPHYSD2, Marfan syndrome, MASS, MFS1, OCTD, SGS, SSKS, Weill Marchesani syndrome, WMS, WMS2

HepG2 cells. Human kidney or placenta.

Molecular Weight: 350kDa

Gene ID: 2200, 591133

UniProt: P35555

Pathways: Maintenance of Protein Location, SARS-CoV-2 Protein Interactome