TCF4 antibody (AA 365-671)

Catalog No. ABIN7863444

The Mouse Monoclonal anti-TCF4 antibody is suitable to detect TCF4 in samples from Human. It has been validated for ELISA and IHC.

Quick Overview for TCF4 antibody (AA 365-671) (ABIN7863444)

Target: TCF4 (Transcription Factor 4 (TCF4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TCF4 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Clone: TCF4-2252

Product Details anti-TCF4 Antibody

Binding Specificity: AA 365-671

Purpose: TCF4 (Transcription Factor 4) Antibody

Specificity: Recognizes a protein of 71kDa, identified as Transcription Factor 4 (TCF4). It is a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human TCF4 protein fragment (around aa 365-671) (exact sequence is proprietary)

Isotype: IgG2c, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for TCF4

Target: TCF4 (Transcription Factor 4 (TCF4))

Alternative Name: TCF4

Background:

bHLHb19, Class B basic helix-loop-helix protein 19, Immunoglobulin transcription factor 2, ITF-2, PTHS, SEF2, SL3-3 enhancer factor 2, TCF4, Transcription factor 4

colon or tonsil., HeLa or HepG2 cells. Human bladder

Molecular Weight: 60kDa

Gene ID: 6925, 605153

UniProt: P15884

Pathways: WNT Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus