DLL3 antibody (AA 400-618)

Catalog No. ABIN7865263

This Mouse Monoclonal antibody specifically detects DLL3 in IHC. It exhibits reactivity toward Human.

Quick Overview for DLL3 antibody (AA 400-618) (ABIN7865263)

Target: DLL3 (delta Like Protein 3 (DLL3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DLL3 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: DLL3-9361

Product Details anti-DLL3 Antibody

Binding Specificity: AA 400-618

Purpose: DLL3 / SCDO1 Antibody

Specificity: This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa400-618) of human DLL3 protein (exact sequence is proprietary)

Isotype: IgG2c, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for DLL3

Target: DLL3 (delta Like Protein 3 (DLL3))

Alternative Name: DLL3

Background:

SCDO1

Human small cell lung cancer or brain.

Molecular Weight: 65kDa

Gene ID: 10683, 127792

UniProt: Q9NYJ7

Pathways: Notch Signaling