Recombinant Villin 1 antibody (AA 600-700)

Catalog No. ABIN7863495

The Rabbit Monoclonal anti-Villin 1 antibody (Clone VIL1-4107R) (ABIN7863495) specifically detects Villin 1 in IHC. The antibody is reactive with Human samples.

Quick Overview for Recombinant Villin 1 antibody (AA 600-700) (ABIN7863495)

Target: Villin 1 (VIL1)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Villin 1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: VIL1-4107R

Product Details anti-Villin 1 Antibody

Binding Specificity: AA 600-700

Purpose: Recombinant Villin (GI-Mucosal & Urogenital Brush Border Marker) Antibody

Specificity: Recognizes a protein of 95 kDa, which is identified as villin. It is a major constituent in the microvilli, which compose the brush border of epithelial cells forming absorptive surfaces of the intestinal and renal proximal tubular epithelia. Anti-Villin labels the brush border area in the gastrointestinal mucosal epithelium and urogenital tract. Among neoplasms, villin is predominantly expressed in tumors of colorectal origin. Antibody to villin is useful in identifying malignant cells from primary and metastatic colorectal carcinomas. This antibody also labels Merkel cells of the skin.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa600-700) of human Villin protein (exact sequence is proprietary)

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for Villin 1

Target: Villin 1 (VIL1)

Alternative Name: Villin

Background:

VIL1, Villin-1, Villin1

A549, HepG2 or HCT116 cells. Human colon or rectum.

Molecular Weight: 93kDa

Gene ID: 7429, 654595

UniProt: P09327

Pathways: EGFR Signaling Pathway, Regulation of Actin Filament Polymerization