Recombinant TRPS1 antibody (AA 900-1100)

Catalog No. ABIN7864197

The Rabbit Monoclonal anti-TRPS1 antibody is suitable to detect TRPS1 in samples from Human. It has been validated for IHC.

Quick Overview for Recombinant TRPS1 antibody (AA 900-1100) (ABIN7864197)

Target: TRPS1 (Trichorhinophalangeal Syndrome I (TRPS1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This TRPS1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: TRPS1-8008R

Product Details anti-TRPS1 Antibody

Binding Specificity: AA 900-1100

Purpose: Recombinant TRPS1 (Transcriptional repressor GATA binding 1) Antibody

Specificity: Transcriptional repressor. Binds specifically to GATA sequences and represses expression of GATA-regulated genes at selected sites and stages in vertebrate development. Regulates chondrocyte proliferation and differentiation. Executes multiple functions in proliferating chondrocytes, expanding the region of distal chondrocytes, activating proliferation in columnar cells and supporting the differentiation of columnar into hypertrophic chondrocytes. Ubiquitously expressed in the adult. Found in fetal brain, lung, kidney, liver, spleen and thymus. More highly expressed in androgen-dependent than in androgen-independent prostate cancer cells.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa900-1100) of human TRPS1 protein (exact sequence is proprietary)

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for TRPS1

Target: TRPS1 (Trichorhinophalangeal Syndrome I (TRPS1))

Alternative Name: TRPS1

Background:

GC79, LGCR, Transcriptional repressor GATA binding 1, Tricho-rhino-phalangeal syndrome type I protein, Trichorhinophalangeal syndrome I, Trichorhinophalangeal syndrome I homolog, TRPS 1, trpS1, TRPS1 gene, TRPS1_HUMAN, Zinc finger protein GC79, Zinc finger transcription factor TRPS 1 antibody

Human squamous epithelium, breast or breast cancer

Molecular Weight: 142kDa

Gene ID: 7227, 657018

UniProt: Q9UHF7

Pathways: Protein targeting to Nucleus