Liver Arginase antibody (Arg1)

Catalog No. ABIN7865213

This Mouse Monoclonal antibody specifically detects Liver Arginase in WB and IHC. It exhibits reactivity toward Human, Rat, Mouse, Guinea Pig and Hamster.

Quick Overview for Liver Arginase antibody (Arg1) (ABIN7865213)

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Reactivity: Human, Rat, Mouse, Guinea Pig, Hamster

Host: Mouse

Clonality: Monoclonal

Conjugate: This Liver Arginase antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: ARG1-9448

Product Details anti-Liver Arginase Antibody

Binding Specificity: AA 11-97, Arg1

Purpose: Arginase 1 (Hepatocellular Carcinoma Marker) Antibody

Specificity: Recognizes a protein of 35-38 kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes, which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human ARG1 protein fragment (around aa11-97) (exact sequence is proprietary)

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for Liver Arginase

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Alternative Name: Arginase 1

Background:

Arginase 1, ARG1, liver-type arginase, type I arginase

Human Liver, Mouse Liver, Rat Liver, Hamster Liver or Guinea pig Liver

Molecular Weight: 35-38kDa

Gene ID: 383, 440934

UniProt: P05089

Pathways: Cellular Response to Molecule of Bacterial Origin