Annexin A2 antibody

Catalog No. ABIN7864756

The Mouse Monoclonal anti-Annexin A2 antibody is suitable to detect Annexin A2 in samples from Human. It has been validated for IHC.

Quick Overview for Annexin A2 antibody (ABIN7864756)

Target: Annexin A2 (ANXA2)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Annexin A2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: 3D5-4

Product Details anti-Annexin A2 Antibody

Purpose: Annexin A2 Antibody

Specificity: The Annexin family of calcium-binding proteins is composed of at least ten mammalian genes and is characterized by a conserved core domain which binds phospholipids in a Ca2+-dependent manner and a unique amino-terminal region which may confer binding specificity. The interaction between these proteins and biological membranes has led to the hypothesis that they are involved in cellular trafficking processes such as endocytosis, exocytosis and cellular adhesion. Annexin I, alternatively referred to as lipocortin, has been implicated as a mediator of the anti-inflammatory response produced by glucocorticoids and as an inhibitor of cPLA2, a potent mediator of inflammation. Annexin II, also called p36, exists as a monomer or as a heterotetramer, complexed with the S-100-related protein p11. This complex is termed Calpactin I. In the tetrameric form, Annexin II is an efficient substrate of PKC family and Src pp60.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human Annexin A2 protein

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for Annexin A2

Target: Annexin A2 (ANXA2)

Alternative Name: Annexin A2

Background:

Annexin A2, Annexin II, heavy chain, ANX2, ANX2L4, arylsulfatase B, CAL1H, calpactin I heavy polypeptide (p36), Calpactin I heavy polypeptide, chromobindin 8, Epididymis secretory protein Li 270, HEL S 270, LIP2, Lipocortin II, LPC2, LPC2D, P36 protein, PAP-IV, Placental anticoagulant protein IV, Protein I

HeLa or A549 cells. Human colon cancer.

Molecular Weight: 36kDa

Gene ID: 302, 511605

Pathways: S100 Proteins