CD79b antibody

Catalog No. ABIN7864895

The Mouse Monoclonal anti-CD79b antibody is suitable to detect CD79b in samples from Human. It has been validated for IHC and ELISA.

Quick Overview for CD79b antibody (ABIN7864895)

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD79b antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Clone: CD79b-4960

Product Details anti-CD79b Antibody

Purpose: CD79b (B-Cell Marker) Antibody

Specificity: CD79 (also designated Ig ±/Ig ≤) is a heterodimer composed of ± chains, designated CD79A or MB-1, and ≤ chains, designated CD79B or B29. The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment of human CD79b protein (exact sequence is proprietary)

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for CD79b

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Alternative Name: CD79b

Background:

AGM6, B-cell antigen receptor complex-associated protein beta chain, B-cell-specific glycoprotein B29, B29, B29/Ig-beta/CD79b, CD79b, Ig-beta, IGB, Immunoglobulin-associated B29 protein

Daudi or Ramos cells. Germinal center B-cells in a lymph node or tonsil.

Molecular Weight: 39kDa

Gene ID: 974, 89575

Pathways: BCR Signaling