CKM antibody

Catalog No. ABIN7862630

The Mouse Monoclonal anti-CKM antibody (Clone CKMM-3341) (ABIN7862630) specifically detects CKM in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for CKM antibody (ABIN7862630)

Target: CKM (Creatine Kinase, Muscle (CKM))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CKM antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: CKMM-3341

Product Details anti-CKM Antibody

Purpose: Creatine Kinase MM Antibody

Specificity: T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31 % overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length CKM protein

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for CKM

Target: CKM (Creatine Kinase, Muscle (CKM))

Alternative Name: Creatine Kinase MM

Background:

CKM, CKMM, Creatine kinase M, Creatine kinase M chain, Creatine kinase M type, Creatine kinase M-type, Creatine kinase muscle, Creatine kinase, muscle type, M-CK, MCK, Muscle creatine kinase

Human heart tissue. Skeletal muscle lysate.

Molecular Weight: 43kDa

Gene ID: 1158, 334347

UniProt: P06732