CSTB antibody

Catalog No. ABIN7862674

The Mouse Monoclonal anti-CSTB antibody (Clone CPTC-CSTB-3) (ABIN7862674) specifically detects CSTB in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for CSTB antibody (ABIN7862674)

Target: CSTB (Cystatin B (Stefin B) (CSTB))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CSTB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: CPTC-CSTB-3

Product Details anti-CSTB Antibody

Purpose: Cystatin B (Marker of Epithelial Ovarian Cancer Progression) Antibody

Specificity: Cystatin A (also designated STF1, STFA, stefin A or cystatin AS) and cystatin B (also designated PME, CST6, STFB, CPI-B, stefin B and liver thiol proteinase inhibitor) are thiol protease inhibitors that form complexes with papain and the cathepsins B, H, and L. cystatin A, a cytoplasmic protein, is one of the precursor proteins of the cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. cystatin B protects against intracellular proteases leaking out of lysosomes and is primarily expressed in heart, liver and kidney.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human Cystatin B protein

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for CSTB

Target: CSTB (Cystatin B (Stefin B) (CSTB))

Alternative Name: Cystatin B

Background:

CHROW21, CPI-B, CST 6, CSTB, CYTB, Stefin B, EPM1, Liver thiol proteinase inhibitor, PME, STFB, ULD

HEK293T or U-87 MG cells. Human tonsil.

Molecular Weight: 12kDa

Gene ID: 1476, 695

UniProt: P04080

Pathways: Response to Water Deprivation