AKR1C1 antibody

Catalog No. ABIN7865150

The Mouse Monoclonal anti-AKR1C1 antibody (Clone AKR1C1-9319) (ABIN7865150) specifically detects AKR1C1. The antibody is reactive with Human, Guinea Pig and Hamster samples.

Quick Overview for AKR1C1 antibody (ABIN7865150)

Target: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Reactivity: Human, Guinea Pig, Hamster

Host: Mouse

Clonality: Monoclonal

Conjugate: This AKR1C1 antibody is un-conjugated

Application: Please inquire

Clone: AKR1C1-9319

Product Details anti-AKR1C1 Antibody

Purpose: Aldo-keto Reductase Family 1 Member C1 / DD1 Antibody

Specificity: DDH / AKR1C1 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human full-length AKR1C1 protein

Isotype: IgG1, kappa

Application Details

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for AKR1C1

Target: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Alternative Name: Aldo-keto Reductase Family 1 Member C1

Background:

2-dihydrobenzene-1, 2-diol dehydrogenase, 20 alpha (3 alpha) hydroxysteroid dehydrogenase, 20ALPHAHSD, 2ALPHAHSD, AK1C1, C9, Chlordecone reductase homolog HAKRC, DD1/DD2, DDH1, Dihydrodiol dehydrogenase 1/2, H37, HBAB, Hepatic dihydrodiol dehydrogenase, High affinity hepatic bile acid-binding protein, Indanol dehydrogenase, MBAB, Trans-1,2 dihydrobenzene 1,2 diol dehydrogenase, Type II 3 alpha hydroxysteroid dehydrogenase

Human liver or stomach tissue. Hamster Liver, Guinea pig Liver or Hep G2

Molecular Weight: 37kDa

Gene ID: 1645, 460260

UniProt: Q04828

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process