GTF2H2C antibody

Catalog No. ABIN7863485

The Mouse Monoclonal anti-GTF2H2C antibody (Clone PCRP-GTF2H2C-2C9) (ABIN7863485) specifically detects GTF2H2C in WB, IHC, IF and FACS. The antibody is reactive with Human samples.

Quick Overview for GTF2H2C antibody (ABIN7863485)

Target: GTF2H2C (General Transcription Factor IIH, Polypeptide 2C (GTF2H2C))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GTF2H2C antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-GTF2H2C-2C9

Product Details anti-GTF2H2C Antibody

Purpose: GTF2H2C (Transcription Factor) Antibody

Specificity: Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription factors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFIIH. TFIIH (or BTF2) is a multisubunit transcription/DNA repair factor that possesses several enzymatic activities. The core of TFIIH is composed of five subunits, designated p89 (XPB or ERCC3), p62, p52, p44 and p34. Additional subunits of the TFIIH complex are p80 (XPD or ERCC2) and the ternary kinase complex composed of Cdk7, cyclin H and MAT1. Both p89 and p80 have ATP-dependent helicase activity. The p62, p52 and p44 subunits have been shown to be involved in nucleotide excision repair.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human GTF2H2C protein

Isotype: IgG2c

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for GTF2H2C

Target: GTF2H2C (General Transcription Factor IIH, Polypeptide 2C (GTF2H2C))

Alternative Name: GTF2H2C

Background:

EVR6, PFM14, PR domain zinc finger protein 17 (PRDM17), RP72, Zinc finger protein 408 (GTF2H2C)

HeLa or Raji cells. Human breast or prostate carcinoma.

Molecular Weight: 44kDa

Gene ID: 730394, 422901

UniProt: Q6P1K8