Recombinant Growth Hormone 1 antibody

Catalog No. ABIN7861386

The Rabbit Monoclonal anti-Growth Hormone 1 antibody is suitable to detect Growth Hormone 1 in samples from Human. It has been validated for IHC.

Quick Overview for Recombinant Growth Hormone 1 antibody (ABIN7861386)

Target: Growth Hormone 1 (GH1)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Growth Hormone 1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: GH-8136R

Product Details anti-Growth Hormone 1 Antibody

Purpose: Recombinant Growth Hormone (Pituitary Marker) Antibody

Specificity: Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human GH1 protein

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for Growth Hormone 1

Target: Growth Hormone 1 (GH1)

Alternative Name: Growth Hormone

Background:

GH-N, GH1, Growth hormone 1, HG1, hGH-N, IGHD1B, Pituitary growth hormone, RNGHGP, Somatotropin

Pituitary cells. Human pituitary tissue (IHC).

Molecular Weight: 20kDa

Gene ID: 2688, 655229

UniProt: P01241

Pathways: NF-kappaB Signaling, JAK-STAT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process