IGF2BP2 antibody

Catalog No. ABIN7865030

The Mouse Monoclonal anti-IGF2BP2 antibody is suitable to detect IGF2BP2 in samples from Human. It has been validated for FACS.

Quick Overview for IGF2BP2 antibody (ABIN7865030)

Target: IGF2BP2 (Insulin-Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IGF2BP2 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: PCRP-IGF2BP2-1F9

Product Details anti-IGF2BP2 Antibody

Purpose: IGF2BP2 Antibody

Specificity: IGF2BP2 (Insulin-like growth factor 2 mRNA binding protein 2) is also known as IGF2 mRNA-binding protein 2, IMP-2 (IGF-II mRNA-binding protein 2), VICKZ family member 2 or hepatocellular carcinoma autoantigen p62 and is a 556 amino acid protein. IGF2BP2 is expressed in a variety of tissues including heart, placenta, skeletal muscle, pancreas, fetal liver, lung, kidney, thymus and gonadal cells. IGF2BP2 is an RNA binding protein which may be involved in the regulation of mRNA translation and may also function to control the spatial localization of target mRNAs. Antibodies against IGF2BP2 have been detected in patients with HCC (hepatocellular carcinoma), suggesting that IGF2BP2 may have a role in the pathogenesis of HCC. Defects in IGF2BP2 are thought to be associated with susceptibility to type two diabetes mellitus.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human IGF2BP2 protein

Isotype: IgG2, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for IGF2BP2

Target: IGF2BP2 (Insulin-Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2))

Alternative Name: IGF2BP2

Background:

Hepatocellular carcinoma autoantigen p62, IGF 2 mRNA binding protein 2, IGF II mRNA binding protein 2, IMP2, Insulin like growth factor 2 mRNA binding protein 2, p62, VICKZ 2, VICKZ family member 2, VICKZ2

HeLa cells.

Molecular Weight: 105kDa

Gene ID: 10644, 35354

UniProt: Q9Y6M1