IL-25 antibody

Catalog No. ABIN7863393

The Mouse Monoclonal anti-IL-25 antibody is suitable to detect IL-25 in samples from Human. It has been validated for IHC.

Quick Overview for IL-25 antibody (ABIN7863393)

Target: IL-25 (IL25) (Interleukin 25 (IL25))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-25 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: IL25-625

Product Details anti-IL-25 Antibody

Purpose: Interleukin-25 (IL-25) / IL-17E Antibody

Specificity: Cytokines are small, soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regulatory function over the immune system and mediate aspects of inflammatory response. They exert their biological effects through the binding of membrane-bound receptors which, in turn, initiate signal transduction cascades and elicit physiological changes in their target cell. Interleukin-17 (IL-17) and its cognate receptor, IL-17R, are an example of such a cytokine receptor pair. Originally identified as a rodent cDNA termed CTLA8, IL-17 is capable of inducing the secretion of IL-6 and IL-8 and augmenting the expression of ICAM-1 in human fibroblast cultures. The IL-17 protein exhibits a striking degree of homology with the HSV-13 protein which mimics its function. The IL-17 receptor is a type I transmembrane protein 864 amino acids in length that is highly expressed in spleen and kidney.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment of human IL25 protein (exact sequence is proprietary)

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for IL-25

Target: IL-25 (IL25) (Interleukin 25 (IL25))

Alternative Name: Interleukin-25

Background:

IL-17E, IL-25, IL17e, IL25, Interleukin 17E, Interleukin 25, Interleukin-17E

Human brain, kidney or lung.

Molecular Weight: 20kDa

Gene ID: 64806, 302036