Recombinant Mammaglobin antibody

Catalog No. ABIN7861684

The Rabbit Monoclonal anti-Mammaglobin antibody (Clone MGB-4812R) (ABIN7861684) specifically detects Mammaglobin in IHC. The antibody is reactive with Human samples.

Quick Overview for Recombinant Mammaglobin antibody (ABIN7861684)

Target: Mammaglobin

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Mammaglobin antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: MGB-4812R

Product Details anti-Mammaglobin Antibody

Purpose: Recombinant Mammaglobin (SCGB2A2) (Breast Cancer Marker) Antibody

Specificity: Mammaglobin, 10 kDa, is a cytoplasmic protein, a mammary-specific member of the uteroglobin family. It is related to a family of epithelial secretory proteins that includes prostatein and Clara cell protein.Mammaglobin occurs in about 80 % of breast carcinomas. The extend is generally larger than that of GCDFP-15. Up to 15 % of nonbreast carcinomas (such as stomach, lung, colon, hepatobiliary, thyroid, ovarian, and urothelial carcinomas) have been reported positive, usually only focally. Mammaglobin is a sensitive and fairly specific marker for breast carcinoma. The panel should also include Gross cystic disease fluid protein-15 and Estrogen receptor alpha.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human Mammaglobin (SCGB2A2) protein

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for Mammaglobin

Target: Mammaglobin

Background:

Mammaglobin-1 (MGB1), Mammaglobin-A, Secretoglobin family 2A member 2 (SCGB2A2), SG2A2, UGB2

HeLa, MCF-7 or T47D cells. Human breast carcinoma.

Molecular Weight: 10.5kDa

Gene ID: 4250, 46452

UniProt: Q13296