NECAB1 antibody

Catalog No. ABIN7861814

This Mouse Monoclonal antibody specifically detects NECAB1 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for NECAB1 antibody (ABIN7861814)

Target: NECAB1 (N-terminal EF-Hand Calcium Binding Protein 1 (NECAB1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NECAB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: NECAB1-7680

Product Details anti-NECAB1 Antibody

Purpose: NECAB1 / N-terminal EF-hand calcium binding protein 1 Antibody

Specificity: Members of the EF-CBP (N-terminal EF-hand calcium binding protein)/NECAB (neuronal calcium-binding protein) family participate in neuronal calcium signaling. EF-CBP1 (N-terminal EF-hand calcium binding protein 1), also known as STIP-1 or neuronal calcium-binding protein 1 (NECAB1), is a 351 amino acid cytoplasmic protein that contains one antibiotic biosynthesis monooxygenase (ABM) domain and 2 EF-hand domains. Expressed in brain, EF-CBP1 interacts with copine 6 and Syntaxin, and exists as two alternatively spliced isoforms. The gene encoding EF-CBP1 maps to human chromosome 8, which consists of nearly 146 million base pairs, encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human NECAB1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for NECAB1

Target: NECAB1 (N-terminal EF-Hand Calcium Binding Protein 1 (NECAB1))

Alternative Name: NECAB1

Background:

EF-hand calcium-binding protein 1, EFCBP1, N-terminal EF-hand calcium-binding protein 1, Neuronal calcium-binding protein 1, STIP-1, synaptotagmin interacting protein 1

Human cerebral cortex, Brain

Molecular Weight: 41kDa

Gene ID: 64168, 642655

UniProt: Q8N987