NEUROD2 antibody

Catalog No. ABIN7863188

The Mouse Monoclonal anti-NEUROD2 antibody (Clone PCRP-NEUROD2-1G1) (ABIN7863188) specifically detects NEUROD2 in ELISA, IF and FACS. The antibody is reactive with Human samples.

Quick Overview for NEUROD2 antibody (ABIN7863188)

Target: NEUROD2 (Neurogenic Differentiation 2 (NEUROD2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NEUROD2 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-NEUROD2-1G1

Product Details anti-NEUROD2 Antibody

Purpose: NEUROD2 (Neurogenic Differentiation 2) (Transcription Factor) Antibody

Specificity: Members of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes, both of which work together to activate DNA transcription. Class A proteins include the ubiquitously expressed E-box binding factors, namely E2A, ITF-2 and HEB, while class B proteins, such as MyoD, myogenin and Neuro D ( æ2), are transiently expressed and exhibit a much more limited tissue distribution. Working in opposition to these positively acting factors are a specialized group of basic helix-loop-helix(bHLH) transcription factorsthat function as dominant negative regulators and are involved in cell lineage determination and differentiation. Neuro D2 (neurogenic differentiation 2), also known as NDRF, NEUROD2 or bHLHa1, is a 382 amino acid nuclear protein that contains one bHLH domain and functions to induce neurogenic differentiation, playing an important role in the maintenance and determination of cell fate.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human NEUROD2 protein

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for NEUROD2

Target: NEUROD2 (Neurogenic Differentiation 2 (NEUROD2))

Alternative Name: NEUROD2

Background:

bHLHa1, class A basic helix loop helix protein 1, NDR2, NDRF, NeuroD-related factor, NeuroD2, neurogenic basic helix loop helix protein, neurogenic differentiation 2, Neurogenic differentiation factor 2, neuronal differentiation 2

HeLa cells. Human brain.

Molecular Weight: ~41kDa

Gene ID: 4761, 322431

UniProt: Q15784