PAX5 antibody

Catalog No. ABIN7861882

The Mouse Monoclonal anti-PAX5 antibody (Clone PCRP-PAX5-1B7) (ABIN7861882) specifically detects PAX5 in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for PAX5 antibody (ABIN7861882)

Target: PAX5 (Paired Box 5 (PAX5))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PAX5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: PCRP-PAX5-1B7

Product Details anti-PAX5 Antibody

Purpose: PAX5 / BSAP (Early B-Cell Marker) Antibody

Specificity: The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. The PAX5 gene is a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding domain, known as the paired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis, therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human PAX5 protein

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for PAX5

Target: PAX5 (Paired Box 5 (PAX5))

Alternative Name: PAX5

Background:

B cell lineage specific activator, BSAP, EBB-1, KLP, Paired box 5

DAUDI or Ramos cells. Human tonsil|lymph node or colon carcinoma.|Raji|spleen

Molecular Weight: 42kDa

Gene ID: 5079, 654464

UniProt: Q02548