PHPT1 antibody

Catalog No. ABIN7861925

This Mouse Monoclonal antibody specifically detects PHPT1 in IHC. It exhibits reactivity toward Human.

Quick Overview for PHPT1 antibody (ABIN7861925)

Target: PHPT1 (phosphohistidine Phosphatase 1 (PHPT1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PHPT1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: PHPT1-12054

Product Details anti-PHPT1 Antibody

Purpose: PHPT1 Antibody

Specificity: PHPT1 (phosphohistidine phosphatase 1), also known as 14 kDa phosphohistidine phosphatase, is a 125 amino acid enzyme belonging to the Janus protein family. Existing as a monomer in the cytoplasm, PHPT1 is an EDTAinsensitive phosphohistidine phosphatase. First identified in human adrenal gland, PHPT1 is highly expressed in skeletal muscle and heart, with lower expression in liver, pancreas and kidney. Overexpression of PHPT1 leads to specific phosphohistidine phosphatase activity towards phosphopeptide I, with no activity detected towards phosphotyrosine, phosphothreonine and phosphoserine peptides. PHPT1 is highly conserved among species, suggesting that it serves an essential functional role.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human PHPT1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for PHPT1

Target: PHPT1 (phosphohistidine Phosphatase 1 (PHPT1))

Alternative Name: PHPT1

Background:

bA216L13.10, CGI-202, DKFZp564M173, HSPC141, PHP14

Human heart, skeletal muscle or breast.

Molecular Weight: 14kDa

Gene ID: 29085

UniProt: Q9NRX4

Pathways: Positive Regulation of Peptide Hormone Secretion